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NIH posts modifications to proposal application and review process

Monday, March 31, 2025

How one applies and has their proposal reviewed to gain a small share of the world's largest funding source for life science research is changing. The following highlights modifications affecting grant applications submitted to the National Institutes of Health for due dates on or after January 25, 2025, as posted on their Implementation of New Initiatives and Policies page.

  • Read more about NIH posts modifications to proposal application and review process

Would an increase in the quantity of NIH SBIR awards impact their overall quality?

Thursday, October 27, 2022

In a recent study titled Does NIH select the right healthcare ventures through the SBIR grant program?, researchers from Rutgers University and the University of Connecticut took advantage of the 2009 American Recovery and Reinvestment Act (ARRA) to conduct a natural experiment.

In a recent study titled Does NIH select the right healthcare ventures through the SBIR grant program?, researchers from Rutgers University and the University of Connecticut took advantage of the 2009 American Recovery and Reinvestment Act (ARRA) to conduct a natural experiment. The opportunity was available due to the National Institutes of Health (NIH) decision to use ARRA dollars to fund additional Phase I SBIR awards from general SBIR competitions, and the researchers compared these 19 ARRA-funded awards to the other 479 Phase I awards that were first funded in the same competitions with regular appropriations.

  • Read more about Would an increase in the quantity of NIH SBIR awards impact their overall quality?

NIH activates new funding vehicle for COVID-19 R&D, other measures seek more information

Thursday, March 12, 2020

For the first time and in response to the COVID-19 outbreak, the National Institute of Allergy and Infectious Diseases (NIAID) together with the National Institute of General Medical Sciences (NIGMS) has activated the NIH Urgent Award mechanism. The targeted opportunity is intended to provide funds for NIH grantees applying to expand the scope of their active grant.

  • Read more about NIH activates new funding vehicle for COVID-19 R&D, other measures seek more information

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Recent news from the SSTI Digest

Differences in industry concentrations of VDO and VC investments

Wednesday, August 26, 2026
Data reveal that policymakers should not equate strong Venture Development Organizations (VDOs) with private venture capital companies; the purpose of creating public policy to increase the availability of innovation-centered risk capital can be lost if one presumes VCs and VDOs are the same. While there are many similarities between individual VDOs and VC funds, important differences in industry concentration emerge when the two groups are compared in aggregate, which may result in different long-term economic impacts.  Effective VDOs are important drivers of regional innovation and of pushing emerging tech businesses forward. VC, on the other hand, can play an extractive role, particularly in markets with scarce equity finance options.
venture capital
venture dev orgs

What could a “new golden age” of science mean for research and commercialization?

Wednesday, August 26, 2026
SSTI’s recent TBED Community of Practice webinar took up a practical question raised by the White House Office of Science and Technology Policy report, Science: A New Golden Age: if federal science policy shifts, what changes will universities, commercialization, and regional innovation organizations need to make? The presentation outlined a research system that could look considerably different from the one that has developed since Vannevar Bush’s Science, the Endless Frontier.
research
commercialization
TBED

New federal rules, both proposed and finalized, will impact small businesses

Thursday, August 27, 2026
A recent flurry of new rules, both proposed and finalized, may interest small business owners or those who advise them. The U.S. Small Business Administration (SBA) has proposed two new rules. The first, Revised Size Standards Methodology, will update SBA’s methodology for determining which businesses qualify as “small.” The second, on Small Business Size Standards, would consolidate the number of industry-specific size standards and raise size standard thresholds. 
small business
SBA
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