California voters will be at the forefront of a highly controversial issue this November when they are asked to decide on a $3 billion bond issue to fund stem cell research.

Only a handful of metropolitan areas have the critical mass necessary to ensure sustainability of their local biotech communities, according to America’s Biotech and Life Science Clusters, a new study from the Milken Institute. At the top of the list is San Diego, followed closely by Boston and the Raleigh-Durham-Chapel Hill metro area. Only another nine are in the running, the report contends.

The majority of an anonymous gift of $26.5 million to the University of Southern California (USC) will be used to increase the representation of women in the hard sciences and engineering faculty and encourage middle school girls to choose a science pathway in education. Money also will be used to create new faculty positions in the sciences, upgrade laboratories, increase scholarship aid for undergraduates, create new fellowships for graduates and fund child care.

With the goal of developing a common technology agenda among the region’s leaders, the Los Angeles Regional Technology Alliance (larta) has compiled its first regional innovation index benchmarking the area’s strengths and weaknesses in S&T. The Southern California Technology Innovation Index compares the five-county Los Angeles consolidated metropolitan statistical area with the California Bay Area (San Francisco, Oakland and San Jose), Austin, Texas, and Massachusetts.

As mentioned in the last week's SSTI Weekly Digest, access to capital is a challenge for women-owned businesses. Springboard 2000, one nationwide initiative to overcome that obstacle, in less than one year, has assisted women entrepreneurs in science and technology businesses to raise more than $235 million in venture funding. The investments have been raised directly as a result of two forums held this year in Redwood City, California and Dulles, Virginia.

During the past two weeks, the Milken Institute has issued two similar reports documenting the difficulties and successes minority- and women-owned business have accessing capital.

The Minority Business Challenge: Democratizing Capital for Emerging Domestic Markets presents new findings and several specific recommendations to sustain minority businesses growth. The findings include:

State science and technology initiatives have been given higher profile in California as the state's lead economic development department changes its name to the Technology, Trade, and Commerce Agency. The new Division of Science, Technology and Innovation, led by Deputy Secretary Joe Raguso, will oversee the state's tech-based economic development efforts.

This summer, North Carolina joined a growing handful of states and regions that have completed innovation assessments or report cards to aid in the development and implementation of state’s science and technology policies. Tracking Innovation: North Carolina Innovation Index 2000 was released in conjunction with a high-tech cluster analysis and a new S&T strategic plan for the state entitled Mapping the Vision.

In a move designed to significantly improve access to higher education, California Governor Gray Davis signed legislation this week that will significantly expand the state's scholarship programs. Under the new legislation nearly one-third of high school graduates will receive scholarship assistance through the state's Cal Grant program, according to the bill's sponsors.

Through its Digital Village Program, Hewlett-Packard is providing up to $15 million in products and resources over a three-year period to three communities who need assistance to participate fully in the New Economy. East Palo Alto, CA already has been designated as a Digital Village; the remaining two will be selected through a competitive process.

The Los Angeles Regional Technology Alliance (larta) has released its 2001 Federal Technology Funding Guide which profiles 89 regularly scheduled federal programs that support technology development and deployment. Each profile includes descriptions, contact information, timelines, and examples. Targeted to technology companies, the guide presents only programs with eligibility requirements open to for-profit businesses. 

Using the microsystems industry in the Southwest as a model, Ross DeVol, Director of Regional and Demographic Studies of the Milken Institute, has written Blueprint for a High-Tech Cluster, a 40-page policy brief on one of the hottest trends for tech-based economic development.

Academic Indirect Cost Rates 

In the late 1980s and early 1990s, as big defense contractors closed their doors and unemployment climbed, San Diego looked as if it might not recover. Between 1990-1993 alone, nearly 60,000 high-paying jobs were lost to defense and aerospace cutbacks. Although the region had some of the ingredients to be successful (defense technologies, a strong university, medical and bioscience institutes, and a desirable climate), the players did not come together to face their economic woes.

Last week, Governor Gray Davis signed into law California’s $99.4 billion budget which provides nearly $305 million for science and technology related programs plus an additional $20 million in research and development tax credits. Specific 

initiatives include:

Forbes magazine, in conjunction with the Milken Institute, released on Monday its second annual "Best Places for Business and Careers" - a ranking of the top 200 metropolitan areas in the United States. The Forbes-Milken Institute list looks at two critical factors to determine which metro areas are the most dynamic: jobs and earnings, and high-technology growth and output.

California's Treasurer Phil Angelides called earlier this month for the nation's largest and third largest pension funds to invest at least $1.5 billion into environmental technologies and environmentally responsible companies.

A new plan to grow North Carolina's biotech industry to 48,000 jobs by 2013 and 125,000 by 2023 was released earlier this month by the North Carolina Biotechnology Center, a state-supported nonprofit organization. If implemented, the 108-page plan would cost up to $650 million over five years. That figure does not include the "to be determined" cost for 15 of the plan's 54 recommendations.

The 54 action steps span a variety of objectives:

The United States Patent and Trademark Office (USPTO) has announced the top 10 U.S. universities receiving the most patents during calendar year 2003. The University of California tops the list for the tenth consecutive year.

Robert Geolas, director of the Centennial Campus at North Carolina State, is resigning to become director of the new International Center for Automotive Research at the Clemson University.

Victor Hwang has been promoted to the position of president at Larta.

Despite a sluggish national economy, North Carolina held its own over the last three years, according to a measure of 25 broad indicators of innovation, technology and economic growth released earlier this week. In all, Tracking Innovation: North Carolina Innovation Index 2003 considers more than 50 performance measures across five general categories, highlighting the state’s strengths and weaknesses.

On Jan. 18, the San Diego Union-Tribune ran a series of three interesting articles examining the biotech sector. One story considers, now that a number of local biotech firms are completing clinical trials, where will they develop their multimillion manufacturing facilities. The other two articles look at selected state and local efforts around the country to support the biotech industry, including Washington, D.C., St. Louis, and Marshfield, WI.

Dr. Catherine Renault is the new program manager for the Center for Technology Applications at RTI International, Inc.

Diane Wirth is new executive director of the Valley Economic Development Corp., a public-private organization for the San Jacinto Valley.