Arizona taxpayers paid at least $100 million for the TGen Institute. The east coast version of Scripps cost Florida a cool $500-plus million. How much should Kansas City expect to pay the Stowers Institute for Medical Research to double the size of its 600,000 sq. ft. research facility instead of locating a second campus elsewhere?

Not a dime.

While rural regions strive to establish basic high-speed Internet connections, larger cities such as St. Louis, Oklahoma City and Roanoke, Va., are looking to establish free, wireless Internet access across several blocks to encourage economic development. Recent reports show efforts are underway to speed the technology's deployment in each of the metro areas.

As the angel investment community continues to evolve from individual investors to sophisticated angel investment groups, the Kauffman Foundation and the Angel Capital Association (ACA) have jointly published a new guide designed to help angels form the most effective angel organizations for their communities.

Kelvin Simmons is the new director of the Missouri Department of Economic Development, replacing Joe Driskell who held the position for 10 years. Simmons had been serving as chairman of the state's Public Service Commission.

The Ewing Marion Kauffman Foundation awarded on Monday $25 million in grants to eight U.S. universities that pledged to make entrepreneurship education available across campus. The selected universities, shown with their award amounts, are:

The Kauffman Foundation of Kansas City announced on Monday it will award grants of up to $5 million to 5-7 U.S. universities to make entrepreneurship education a common and accessible campus-wide opportunity. The Foundation works with partners to encourage entrepreneurship across America.

The St. Louis BioBelt announced this week it is well along in launching four new initiatives designed to position the region as a "location of choice" for start-up and evolving plant and life science companies.

A Blueprint for Prosperity and Jobs, a comprehensive strategic plan to foster and sustain job growth, business success and community vitality in Missouri, has been released by the Missouri Department of Economic Development. The product of two years of research, the plan addresses Missouri's need to focus its resources on building a knowledge-based economy, with emphasis on businesses that generate key technologies and have tremendous growth potential.

Bill Duncan is the first president of the Kansas City Area Life Sciences Institute, which held its inaugural event at the end of March.

The St. Louis region lags behind a number of metropolitan areas including Austin, Portland, Atlanta, and Indianapolis in attracting 20- to 34-year olds to live and work in the region, according to a report released this month by the regional, nonprofit organization, FOCUS St. Louis.

Not all of the pieces critical to building an innovation-based economy have to cost hundreds of millions of dollars, as might be suggested in the Florida and Pennsylvania stories above. Gov. Matt Blunt's Feb. 2 call for the state to provide $2 million for a new Missouri Life Science Incubator - designed to help researchers move their science from the laboratory to commercial businesses - provides a case in point.

Two bills passed by the Missouri General Assembly last week include more than $32 million to support new initiatives to promote TBED activities in the state. Programs to support bio-agricultural research, technology commercialization and business growth won the lion's share of the new appropriations.

Marianne Hudson is leaving her position as Vice President - Marketing & Communications with the Mid-America Manufacturing Technology Center to become a program manager at the Kauffman Center for Entrepreneurial Leadership.