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The new year begins with a layer of both fiscal and political uncertainty. For at least 18 states, it will be a year of change in political leadership. After several years of continuous revenue growth, states are crafting their Fiscal Year (FY) 2027 budgets amid slower growth, rising costs, and heightened unease.

The Maine Technology Institute’s core mission is to use innovation to spur the development of new products, processes, and companies that strengthen the state’s economy. Finishing its 25th year of operations, MTI solidly illustrates how a sustained, focused yet flexible and creative strategy can deliver this mission. MTI has disbursed $387 million across 4,350 distinct projects throughout Maine since its founding, and that funding has leveraged over $2.2 billion in private sector matching investment. 

When Daniel Pelaez took a job with the Town of Southbury, Connecticut Public Works Department after his first year at Worcester Polytechnic Institute, he learned lessons that, a few years later, would become the basis for his startup, Cyvl. Daniel spent a season on the public works road crew fixing issues flagged by residents or found by the road foreman.

Technology-based economic development organizations work with economic development professionals throughout the U.S. to help build their local innovation and entrepreneurship ecosystems. Sometimes, bringing in outside expertise with established networks to R&D and finance can accelerate the local capacity to support innovation-driven startups. gener8tor, a venture capital and startup accelerator founded in Wisconsin, is one such example of external partners supporting TBED capacity building anywhere.

Massachusetts’ Gov. Maura Healey recently proposed a multi-year funding strategy (Five-Year Massachusetts Capital Investment Plan (CIP) [FYs 2026-2030] that  would include investment of $890.4 million, including general obligation bonds and private sector contributions, for many of the state’s TBED and innovation initiatives (programs are outlined below).

Vaccine and therapeutics storage and delivery may never be the same as Emory University and Micron Biomedical recently announced the first clinical trial of a novel rotavirus vaccine, CC24, delivered via dissolvable microarray technology. This clinical trial was the first clinical evaluation of any drug or vaccine delivered via patch or microarray that is sponsored by the U.S. Centers for Disease Control and Prevention (CDC). 

Please note: this article is not intended as a comprehensive review of Public Law No. 119-21, nor should our reading of the law be treated as tax or legal advice.