SSTI Digest

A Feb. 7 memo from the Office of the Director of the National Institutes of Health (NOT-OD-25-068) announced the decision to implement a flat 15% Facilities and Administrative fee (F&A), also known as an indirect cost rate, ”across all NIH grants.” Public statements from the Association of American Medical Colleges (AAMC), Association of American Universities (AAU), American Council on Education, (ACE) and Association of Public and Land-grant Universities (APLU), among others, outlined their objections to the move, highlighting the impact it would have on medical research.

Press coverage has focused on the impact on institutions of higher education, but it is important to note that SBIR grantees will be covered under this directive as well. The notice is contradictory, however, as to when the policy will go into effect for grantees that are not institutions of higher education.  

Answering the question of what impact a flat 15% F&A reimbursement rate would have on the nation’s SBIR startups requires real data. The data doesn’t currently exist that we are aware of. As a result, SSTI invites all SBA FAST recipients, state SBIR matching grant programs, life science-based innovation and commercialization offices, and other interested TBED initiatives to join us for a virtual meeting as we launch a ‘citizen-science based’ online record gathering initiative to help inform state and federal policymakers.  Register here.

SSTI university members will be invited to a zoom later this week. Academic parties interested in attending that call but are not members of SSTI currently may explore membership here.

President Trump’s nominee to become Secretary of Commerce, Howard Lutnick, cleared the Senate Committee on Commerce, Science and Transportation on Feb. 4 by a vote of 16 to 12. A floor vote is expected soon, possibly still this week. Among the agencies within the Commerce Department are two agencies that support core elements of regional innovation and technology-based economic development more broadly. The National Institutes of Standards and Technology (NIST) oversees the Manufacturing Extension Partnership and the Economic Development Administration, which is one of the largest federally supported of core TBED and economic development efforts around the country. Lutnick’s support of the CHIPS Act and sustaining the current structure of the National Oceanic and Atmospheric Administration (NOAA) remain unclear, according to Roll Call. Lutnick is currently CEO of Cantor Fitzgerald, a Wall Street financial services firm.

In this week’s continuing coverage of gubernatorial addresses as they impact the innovation economy, the following highlights have been selected from three of the eight State of the States or budget addresses given between Jan. 28 and Feb. 5, 2025, by the governors from Indiana, Mississippi, and South Carolina. This is the first address for Indiana's new governor, and it provides evidence of economic development being one of his top priorities. Information on previous 2025 State of the States and/or budget addresses can be found here and here.

Upcoming addresses and states will be covered in future Digest issues.

The launch of a new private equity firm in central Ohio is a reminder of the continuing ripple effects of a decades-long strategy of cultivating an innovation system. If the State of Ohio hadn’t created and provided sustained funding over decades for its integrated array of technology-based economic development programs, the founders of a newly launched private equity firm wouldn’t be in the position now to commit to helping more mid-market companies succeed in central Ohio.

Acceptd, an arts-centered platform development company, tapped several different aspects of Ohio’s Third Frontier Program at various times in the startup’s growth cycle before being acquired for a hefty price in 2021. The founders of that company have now launched a private equity firm to acquire middle-market companies.

Readers may have noticed the most populous states end up topping many of the statistical tables related to economic development. Normalizing the data by some relevant, related measure can provide a higher quality look that is a little closer to the “apples to apples” appeal that might help influence some policy issues. For this week’s edition of Useful Stats, SSTI is exploring research intensity as a component of state gross domestic product (GDP) and the research load “carried” by each member of the R&D personnel within the state’s higher education community.

HERD and GDP

Higher education R&D (HERD) intensity as it relates to GDP, calculated as HERD expenditures as a percentage of total GDP, indicates the relative importance of R&D spending by colleges and universities to their regional economies and varies greatly across the U.S. Note that HERD survey data is released by Fiscal Year (FY), while GDP data, drawn from the U.S. Bureau of Economic Analysis (BEA), is released by calendar year.

SSTI’s new analysis of NIH data reveals the agency’s external R&D spending per award has been essentially treading water for the past 25 years in terms of real dollars—rising just 4% since FY 2000 when adjusted for inflation. This slow growth comes despite the crucial role NIH funding plays in technology-based economic development (TBED) policies across many states, particularly in the biomedical and life sciences. However, NIH funding remains a major economic driver as the world’s largest funder of biomedical and behavioral research, having generated nearly $2.50 of economic activity for every dollar spent in FY 2023, according to NIH estimates. While these awards support innovation, academic research, and regional economies, their purchasing power has eroded over time, barely keeping pace with inflation.

Artificial intelligence, market saturation, and shifting demands from both employers and students are driving changes in coding bootcamps and other programs in the tech training sector, according to a recent Inside Higher Education story. These factors have contributed to several closures in the past year:

In this week’s continuing coverage of gubernatorial addresses as they discuss the innovation economy, the following highlights have been selected from five of the eight State of the States or budget addresses given between Jan. 17 and Jan. 28, 2025, by the governors from Maine, Missouri, New Mexico, Utah, and Wisconsin. Information on previous 2025 State of the States and/or budget addresses can be found here.

Additional addresses and states will be covered in future Digest issues.

The U.S. National Science Foundation announced awards totaling approximately $40 million to support research and STEM workforce development in Delaware, Guam, Kentucky, Louisiana, and Vermont, according to a January 22 NSF press release. These grants are part of the NSF Established Program to Stimulate Competitive Research (NSF EPSCoR).

Regional cooperation economic development is believed to stimulate growth in various ways, including increased trade, enhanced movement of technologies from lab to market, and improved resource allocation. Federal support for innovation-driven growth has increasingly forced applicants to take integrated regional approaches. However, empirical evidence on the specific impacts of such cooperation is scant. New research from the IZA Institute of Labor Economics seeks to address this gap by investigating the interplay between regional cooperation and integration (RCI) and two key economic outcomes: labor productivity and firm-level innovation. 

Recent headlines have been full of discussion on cryptocurrencies and speculation on significant changes in federal policy related to the technology. Anticipating federal action, leaders of several states are exploring ways to get their own jurisdictions involved in the space. Here are some recent examples, drawing from proposed legislation to implemented policies and structures for acceptance of the financial innovation:

States Considering Bitcoin Reserves